Cognitive Interventions Targeting Brain Plasticity in the Prodromal and Early Phases of Schizophrenia ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 9 2013; 9: 435-463
Several important paradigm shifts have occurred in the field of schizophrenia treatment, including an increased focus on early detection, the development of preemptive interventions, and the view of schizophrenia as a neurodevelopmental disease characterized by decreased efficiency and abnormal connectivity in cortical and subcortical neural networks. In this review, we briefly describe some of the neural impairments that contribute to the development of schizophrenia, with an emphasis on the impact of stress and trauma on cognitively vulnerable neural systems. We then present current data on two behavioral interventions that target these critical risk factors and that aim to preempt the onset of schizophrenia in vulnerable individuals or improve the clinical course in recent-onset schizophrenia: cognitive therapy and computerized cognitive training.
View details for DOI 10.1146/annurev-clinpsy-032511-143134
View details for Web of Science ID 000321742100018
View details for PubMedID 23297786
Psychosocial interventions for adolescents at clinical high risk for psychosis: cognitive behavioral therapy Adolescent Psychiatry 2012; 2: 172-181
Filling the implementation gap: a community-academic partnership approach to early intervention in psychosis EARLY INTERVENTION IN PSYCHIATRY 2011; 5 (4): 366-374
The aim of this study was to describe the development of a sustainable community early psychosis programme created through an academic-community partnership in the United States to other parties interested in implementing early psychosis services founded upon evidence-based practices within community settings.The service was developed around a sustainable core of key components, founded upon evidence-based practice, with additional flexible elements that could be adapted to the needs of the individual commissioning county. This paper describes the ways in which funding was sourced and secured as well as the partnerships developed through this process.Successful development of the Prevention and Recovery from Early Psychosis (PREP) programme in San Francisco County, California. PREP clinicians have received extensive training in the evidence-based approaches that are available through the programme and treated 30 clients and their families in the first year of operation.Development of a sustainable community programme of this type in a non-universal health-care setting, which is historically seen as non-integrated, required extensive partnering with agencies familiar with local resources. Implementation of the community-academic partnership bridged the gap between research and practice with successful integration of fidelity practice at the community level. The community partners were effective in sourcing funding and allocating resources, while the academic side of the partnership provided training in evidence-based models and oversight of clinical implementation of the model. Stringent evaluation of the impact of the service is our next focus.
View details for DOI 10.1111/j.1751-7893.2011.00310.x
View details for Web of Science ID 000297018400013
View details for PubMedID 22032550
At risk of developing psychosis: the research perspective Experiencing psychosis: personal and professional perspectives Routledge. 2011
Re-envisioning psychosis: a new language for clinical practice Current Psychiatry 2010; 9: 23-28
THE SUBJECTIVE EXPERIENCE OF PEOPLE AT A HIGH RISK OF DEVELOPING PSYCHOSIS JOURNEYING INTO AND THROUGH AN EARLY DETECTION FOR PSYCHOSIS SERVICE SCHIZOPHRENIA BULLETIN 2009; 35: 309-310