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Katherine McCallie, MD

  • Katherine R McCallie

Specialties

Neonatal-Perinatal Medicine

Work and Education

Professional Education

University of Pennsylvania School of Medicine, Philadelphia, PA, 2002

Internship

University of Washington Childrens Hospital & Regional Medical Center, Seattle, WA, 2003

Residency

University of Washington Childrens Hospital & Regional Medical Center, Seattle, WA, 2005

Fellowship

Lucile Packard Children's Hospital, Palo Alto, CA, 06/30/2010

Board Certifications

Neonatal-Perinatal Medicine, American Board of Pediatrics

Pediatrics, American Board of Pediatrics

Services

Neonatology

All Publications

Feeding Protocols for VLBW Infants Neonatology: Clinical Practice and Procedures McCallie, K. edited by Stevenson, D., Cohen, R., Sunshine, P. McGraw-Hill Education. 2015; 1st ed.: 1017-1020
Inhaled Nitric Oxide Neonatology: Clinical Practice and Procedures McCallie, K., Van Meurs, K. edited by Stevenson, D., Cohen, R., Sunshine, P. McGraw-Hill Education. 2015; 1st ed.: 1125-1127
Feeding Premature Infants: Why, When, and What to Add to Human Milk JOURNAL OF PARENTERAL AND ENTERAL NUTRITION Cohen, R. S., McCallie, K. R. 2012; 36: 20S-24S
Neonatology Pediatrics for Medical Students Cohen, R., McCallie, K., Rhine, W. edited by Bernstein, D., Shelov, S. Lippincott Williams & Wilkins. 2012; 3rd ed.: 223-250
Improved outcomes with a standardized feeding protocol for very low birth weight infants JOURNAL OF PERINATOLOGY McCallie, K. R., Lee, H. C., Mayer, O., Cohen, R. S., Hintz, S. R., Rhine, W. D. 2011; 31: S61-S67

Abstract

The objective of this study was to evaluate the impact of a standardized enteral feeding protocol for very low birth weight (VLBW) infants on nutritional, clinical and growth outcomes.Retrospective analysis of VLBW cohorts 9 months before and after initiation of a standardized feeding protocol consisting of 6-8 days of trophic feedings, followed by an increase of 20?ml/kg/day. The primary outcome was days to reach full enteral feeds defined as 160?ml/kg/day. Secondary outcomes included rates of necrotizing enterocolitis and culture-proven sepsis, days of parenteral nutrition and growth end points.Data were analyzed on 147 VLBW infants who received enteral feedings, 83 before ('Before') and 64 subsequent to ('After') feeding protocol initiation. Extremely low birth weight (ELBW) infants in the After group attained enteral volumes of 120?ml/kg/day (43.9 days Before vs 32.8 days After, P=0.02) and 160?ml/kg/day (48.5 days Before vs 35.8 days After, P=0.02) significantly faster and received significantly fewer days of parenteral nutrition (46.2 days Before vs 31.3 days After, P=0.01). Necrotizing enterocolitis decreased in the After group among VLBW (15/83, 18% Before vs 2/64, 3% After, P=0.005) and ELBW infants (11/31, 35% Before vs 2/26, 8% After, P=0.01). Late-onset sepsis decreased significantly in the After group (26/83, 31% Before vs 6/64, 9% After, P=0.001). Excluding those with weight <3rd percentile at birth, the proportion with weight <3rd percentile at discharge decreased significantly after protocol initiation (35% Before vs 17% After, P=0.03).These data suggest that implementation of a standardized feeding protocol for VLBW infants results in earlier successful enteral feeding without increased rates of major morbidities.

View details for DOI 10.1038/jp.2010.185

View details for Web of Science ID 000289236900010

View details for PubMedID 21448207