Oral Medicated Cycle

This is the simplest and most common form of treatment used in women who do not ovulate or who ovulate infrequently. It is also a very common initial treatment for couples with unexplained infertility. These medications are in the form of tablets which are taken daily by mouth for five days. Clomiphene and Letrozole are the two more commonly used oral medications. Your physician will determine the medication most suitable for you. Most women do not suffer any side effects with these medications. However, some women may have side effects such as mood changes, bloating, breast tenderness, or hot flashes. Risk of multiple pregnancies depends on the number of oocytes released (which can be predicted by ultrasound) and age.

Baseline ultrasound is performed before starting oral medications. Occasionally there may be an ovarian cyst detected at this time. If a cyst is detected, you will be instructed not begin treatment. If there are no cysts present, you will be asked to take your medication.

A decision making ultrasound will be performed mid-cycle to check for follicular development. When the ultrasound examination suggests that the eggs are mature (usually when the lead follicle size is about 20 mm or greater in diameter), you will be instructed to take an injection of human chorionic gonadotropin (HCG). The timing of the HCG is critical, so it is crucial that you take it at the time instructed. This injection is administered subcutaneously similar to the one used to administer insulin and the method to administer the injection is covered in the Orientation class. Approximately 36 to 41 hours after the HCG injection, an IUI will be performed.
Two weeks following the IUI a pregnancy test is performed to determine if the IUI was successful.

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