Uterine Microbiome in Early Pregnancy

This clinical research study will investigate whether an abnormal microbiome of the uterus can cause miscarriage. The microbiome is a collection of trillions of tiny organisms, including bacteria, fungi and viruses, which live throughout the body. The role of the microbiome in health and disease states is an active area of investigation in multiple fields across medicine. Our study examines the role of the microbiome of the uterus in miscarriage.

Who is eligible to participate?

  • Any patient diagnosed with a missed abortion electing to undergo a dilation and curettage (D&C) procedure

Study participation involves:

  • At the time of the D&C procedure, testing of excess pregnancy tissue for microbiome
  • Chromosome testing of miscarriage tissue
  • Peripheral blood collection at time of D&C
  • Follow-up collection of uterine fluid in the office six to eight weeks after the D&C

Study results are not disclosed to patients because this is a preliminary study. Enrolled participants will receive testing free of charge.

For more information, please contact:

Fertility and Reproductive Health logo