Recurrent Pregnancy Loss

If you’ve experienced a miscarriage, you’re not alone. Miscarriage (the loss of pregnancy before viability) is the most common pregnancy complication, and studies show that about 25% of all women experience at least one miscarriage in their lives.

Recurrent pregnancy loss (RPL) or recurrent miscarriage (RM) affects 1% to 5% of reproductive-age couples. This can be emotionally challenging and confusing. There are many causes and contributing factors to consider in a pregnancy loss evaluation. Yet, despite a comprehensive evaluation, a definitive cause is found in fewer than half of the couples experiencing repeated pregnancy loss.

The distress associated with unexplained recurrent miscarriages often leads patients to question their ability to successfully conceive and have a baby, and couples often find themselves drawn to unproven testing and treatments. However, studies show that with an evidence-based approach and supportive care, most couples have a very good chance of a successful pregnancy.

We are here to answer your questions and give you the best care that modern medicine can offer. It starts with optimizing your overall health before conceiving, with the goal of giving you the best chances for a successful, sustained pregnancy. Since our program started in 2009, we have helped hundreds of women go on to have healthy babies.

Trying to Conceive after Repeat Miscarriages

Headshot of Ruth Lathi, MD. Click to watch videoPlay

Stanford’s Ruth Lathi, MD, explains the factors that may cause repeat miscarriages, the timing for physical and emotional recovery, and shares resources to help support women through this difficult process.

Watch video >

Our Unique Approach

Causes of recurrent miscarriage can be multifactorial, such as medical, genetic, anatomic, hormonal, and immunologic abnormalities. This is why we put a multidisciplinary team behind your testing and treatment. Understanding the physical and psychological consequences of miscarriage is a central focus of our team.

Our specialists work together to identify causes of pregnancy loss and to create individualized, unique approaches to caring for each patient. Your care team could include specialists in perinatal geneticsmaternal-fetal medicine (high-risk obstetrics), hematologyimmunologyurology (to examine male causes), endocrinologysocial work, adult psychology, and many more.

These specialists collaborate to fully understand what could be contributing to the miscarriages and to find the best way to address it. If the miscarriages are still unexplained, our female patients can enroll in clinical trials to get one step closer to finding out the cause and, hopefully, be able to conceive a healthy baby. This highly collaborative and holistic approach of our Recurrent Pregnancy Loss program team is unique, and we are the only program in country with this level of multidisciplinary integration.

Miscarriage can have a profound impact on your sense of well-being. Depression and anxiety are common in the months following the loss of a pregnancy and can last for a year or more. Be sure to talk to your provider about your concerns, anxiety, or depression.

For questions or to schedule consultations with our Fertility and Reproductive Health–Recurrent Pregnancy Loss Program, call (844) 661-9857.


The physicians at Stanford Medicine Children’s Health are actively engaged in research focusing on recurrent pregnancy loss, as well as related topics including reproductive genetics and the role of preimplantation genetic testing of embryos, pregnancy health after infertility and assisted reproduction, and endometrial factors involved in implantation and early pregnancy.

Learn more about our recurrent pregnancy loss research and how you can get involved >

Patient resources

Recurrent Pregnancy Loss Program - Care Team

Reproductive Endocrinology and Infertility (REI) | (650) 498-7911
Ruth Lathi, MD – Medical Director
Lusy Aghajanova, MD, PhD

Maternal Fetal Medicine | (650) 498-4069
Katherine Bianco, MD
Jane Chueh, MD
Maurice Druzin, MD
Virginia Winn, MD

Early Pregnancy Clinic & Complex Family Planning (CFP) | (650) 725-6079
Jade Shorter, MD
Kate Shaw, MD

Women's Wellness Clinic & Psychiatry(650) 498-9111
Katherine Williams, MD
Ripal Shah, MD
Mytilee Vemuri, MD
S Dina Wang-Kraus, MD
Miriam Schultz, MD

Medical Genetics & Perinatal Genetics | (650) 721-5804
Dena Matalon, MD
Christy Tise, MD, PhD

REI Genetic Counseling | (650) 498-7911
Ronit Mazzoni, MS, LCGC

Endocrinology | (650) 721-1300
Chrysoula Dosiou, MD, MS
Sun Kim, MD, MS

Immunology & Rheumatology | (650) 723-6961
Yashaar Chaichian, MD
Audra Horomanski, MD
Julia Simard, ScD

Hematology | (650) 723-5535
May Chien, MD
Marie Hollenhorst, MD

Urology | (650) 723-3391
Michael Eisenberg, MD

Fertility and Reproductive Health logo