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Nichole Wang, DO

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Trabajo y educación

Educación

University of Northern Texas College of Osteopathic Medicine, Fort Worth, TX, 06/21/2013

Últimos años de residencia

Lucile Packard Children's Hospital at Stanford, Palo Alto, CA, 6/30/2016

Certificado(s) de especialidad

Pediatrics, American Board of Pediatrics

Servicios

Neonatología

Todo Publicaciones

Changing Management of the Patent Ductus Arteriosus: Effect on Neonatal Outcomes and Resource Utilization. American journal of perinatology Chock, V. Y., Goel, V. V., Palma, J. P., Luh, T. M., Wang, N. A., Gaskari, S., Punn, R., Silverman, N. H., Benitz, W. E. 2017

Abstract

ObjectiveThis historical cohort study investigated how a shift toward a more conservative approach of awaiting spontaneous closure of the patent ductus arteriosus (PDA) in preterm infants has affected neonatal outcomes and resource utilization. MethodsWe retrospectively studied very low birth weight infants diagnosed with a PDA by echocardiogram (ECHO) in 2006-2008 (era 1), when medical or surgical PDA management was emphasized, to those born in 2010-2012 (era 2) when conservative PDA management was encouraged. Multiple regression analyses adjusted for gestational age were performed to assess differences in clinical outcomes and resource utilization between eras. ResultsMore infants in era 2 (35/89, 39%) compared with era 1 (22/120, 18%) had conservative PDA management (p<0.01). Despite no difference in surgical ligation rate, infants in era 2 had ligation later (median 24 vs. 8 days, p<0.0001). There was no difference in clinical outcomes between eras, while number of ECHOs per patient was the only resource measure that increased in era 2 (median 3 vs. 2 ECHOs, p=0.003). ConclusionIn an era of more conservative PDA management, no increase in adverse clinical outcomes or significant change in resource utilization was found. Conservative PDA management may be a safe alternative for preterm infants.

View details for DOI 10.1055/s-0037-1601442

View details for PubMedID 28376547