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Caroline Okorie, MD

  • Caroline Uchechi Adanma Okorie

I am both a pediatric pulmonologist and sleep specialist, so I have the opportunity to care for a diverse group of patients with a variety of health issues. I provide care for patients starting from when they're neonates up until they're adults. I enjoy educating patients, families and communities about how to best partner with their medical team to optimize our patients' health and quality of life. I strive to empower patients and families to feel that we are all part of a team working to achieve the best outcome. Everyone should feel like they're part of the solution.

Specialties

Asthma

Sleep Disorders

Pulmonary

Work and Education

Professional Education

University of Arizona College of Medicine, Tucson, AZ, 05/15/2010

Residency

Oregon Health & Science University, Portland, OR, 06/30/2014

Fellowship

Stanford University School of Medicine - Office of Graduate Affairs - Postdoctoral Affairs, Stanford, CA, 06/30/2017

Stanford University School of Medicine - Office of Graduate Affairs - Postdoctoral Affairs, Stanford, CA, 06/30/2018

Board Certifications

Pediatric Pulmonary, American Board of Pediatrics

Pediatrics, American Board of Pediatrics

Conditions Treated

Asthma

Sleep Medicine

All Publications

The nocturnal-polysomnogram and "non-hypoxic sleep-disordered-breathing" in children. Sleep medicine Guilleminault, C., Huang, Y., Chin, W., Okorie, C. 2018

Abstract

OBJECTIVE: To characterize sleep-disordered breathing patterns not related to hypoxia resulting in fragmented sleep in children.METHODS: We reviewed the polysomnogram (PSG) data of children with sleep complaints who were being evaluated for sleep-disordered breathing and had an apnea-hypopnea-index3. These data were compared to the recordings of the same children with nasal CPAP administered for one night and to 60 control subjects (children without any sleep complaints). A subgroup of children was monitored with esophageal manometry, but nasal cannula flow data was recorded in all cases.RESULTS: Abnormal breathing patterns, particularly flow limitation, could be seen with more severity and frequency compared to apnea or hypopnea. The observed abnormal breathing patterns were associated with EEG disturbances.CONCLUSIONS: Patterns such as flow-limitation, mouth-breathing, changes in inspiratory and expiratory time, rib-cage and expiratory muscle activity, transcutaneous CO2 electrode changes and snoring noises are all variables that should be systematically reviewed when analyzing nocturnal PSG. Current scoring guidelines emphasizes apnea-hypopnea and hypoxic-sleep disordered breathing and therefore treatment is often much delayed in this population of children with evidence of abnormal breathing patterns. Analysis of the various patterns of abnormal breathing noted above allows recognition of "non-hypoxic" sleep-disordered-breathing (SDB).

View details for DOI 10.1016/j.sleep.2018.11.001

View details for PubMedID 30578113

Diagnosis And Management Of Sporadic Pulmonary Arteriovenous Malformation Not Associated With Hereditary Hemorrhagic Telangiectasia Okorie, C., Bhargava, S. AMER THORACIC SOC. 2016
Allergic Bronchopulmonary Aspergillosis. Journal of fungi (Basel, Switzerland) Tracy, M. C., Okorie, C. U., Foley, E. A., Moss, R. B. 2016; 2 (2)

Abstract

Allergic bronchopulmonary aspergillosis (ABPA), a progressive fungal allergic lung disease, is a common complication of asthma or cystic fibrosis. Although ABPA has been recognized since the 1950s, recent research has underscored the importance of Th2 immune deviation and granulocyte activation in its pathogenesis. There is also strong evidence of widespread under-diagnosis due to the complexity and lack of standardization of diagnostic criteria. Treatment has long focused on downregulation of the inflammatory response with prolonged courses of oral glucocorticosteroids, but more recently concerns with steroid toxicity and availability of new treatment modalities has led to trials of oral azoles, inhaled amphotericin, pulse intravenous steroids, and subcutaneously-injected anti-IgE monoclonal antibody omalizumab, all of which show evidence of efficacy and reduced toxicity.

View details for DOI 10.3390/jof2020017

View details for PubMedID 29376934

View details for PubMedCentralID PMC5753079

A Presentation Of Hepatopulmonary Syndrome In A Five Year Old During Evaluation For Miliary Tuberculosis Okorie, C. U., Mark, J. D. AMER THORACIC SOC. 2015
Successful Treatment Of Mineral Oil Associated Lipoid Pneumonia In An Infant Okorie, C., Powers, M. AMER THORACIC SOC. 2013