Research and Innovation

The Pediatric Arrhythmia program has concentrated on novel electrophysiologic approaches to the diagnosis and treatment of arrhythmias.

1. Improving the safety of ablation therapy for SVT and VT

a) Cutting-edge technology, including 3-D electroanatomic mapping to decrease radiation exposure during ablation

b) Cryotherapy to decrease the risk of heart block and damage to the normal conduction system, which is one of the most troublesome complications known to occur with ablation therapy

2.  Novel methods of placing implantable cardioverter defibrillators (ICD) to protect against sudden death, including implantation in the smallest recorded recipient of an ICD (implanted at 2 days of life)

3. Arrhythmia management tailored to the unique needs of pediatric and congenital heart disease patients with heart failure, including placement of ICDs, as well as innovative use of resynchronization devices to improve heart function and patient survival

4. A dedicated inherited arrhythmias clinic, including a cardiovascular genetics counselor, a pediatric electrophysiologist and a genetics cardiologist, to deliver multidisciplinary care to families with inherited arrhythmias

5. A dedicated pediatric psychologist for assessment of anxiety and depression in patients with ICDs

Our research has concentrated on both the management of arrhythmias in heart failure and the use of resynchronization therapy to improve heart function in pediatric and CHD patients with heart failure:

1. The first multicenter report of resynchronization therapy (biventricular pacing) in children with heart failure (Dubin et al. JACC 2004)

2. The first study that showed the importance of biventricular pacing in patients who are pacemaker dependent with no underlying rhythm (Ceresnak et al Heart Rhythm 2015)

3. The first investigation showing a mortality benefit to resynchronization therapy in children and patients with congenital heart disease

4. The first assessment of patient- and parent-identified needs in pediatric patients with ICDs

Our research also has concentrated on how to improve safety of ablation therapy:

1. Improving outcomes in patients with SVT using cryoablation (Reddy HR 2017)

2. Decreasing radiation exposure in patients undergoing ablation (Ceresnak JCE 2015)