Conditions We Treat

Our Pediatric Liver Center care team provides expert care for all types of pediatric liver disorders, congenital liver defects, liver disease, and disease in related organs, including the gallbladder, pancreas, and biliary tree. We treat common to advanced, complex, and rare liver disease in children of all ages, including very small infants. Conditions include:

Cholestasis and jaundice

  • Biliary atresia
  • Disorder of bilirubin metabolism
  • Conjugated hyperbilirubinemia, direct hyperbilirubinemia, or cholestasis

Genetic and metabolic liver disease

  • Alagille syndrome
  • Progressive familial intrahepatic cholestasis (PFIC)
  • Cystic fibrosis associated liver disease (CFALD)
  • Alpha-1 antitrypsin deficiency
  • Wilson’s disease
  • Zellweger syndrome
  • Metabolic dysfunction-associated fatty liver disease (MAFLD), fatty liver disease
  • Bile acid synthesis defects
  • Glycogen storage disease
  • Lysosomal storage diseases
  • Mitochondrial liver disease
  • Methylmalonic acidemia
  • Propionic acidemia
  • Organic acidemias
  • Urea cycle disorders
  • Ornithine transcarbamylase (OTC) deficiency
  • Citrullinemia
  • Carbamoyl phosphate synthetase 1 (CPS1) deficiency
  • Argininosuccinic aciduria
  • Argininemia
  • Maple syrup urine disease

Diseases of the biliary system 

  • Primary sclerosing cholangitis (PSC)
  • Immunoglobulin G4 (IgG4)-related hepatobiliary disease
  • Biliary cirrhosis
  • Choledochal cyst
  • Caroli syndrome
  • Choledocholithiasis
  • Bile duct obstruction
  • Bile duct stricture
  • Bile leak
  • Gallstones or cholelithiasis

Complications of chronic liver disease

Autoimmune liver disease

  • Autoimmune hepatitis
  • Primary sclerosing cholangitis (PSC)
  • Overlap syndrome
  • Immunoglobulin G4 (IgG4)-related hepatobiliary disease

Liver infections and hepatitis

Liver cancer, masses, and tumors

  • Hepatoblastoma
  • Focal nodular hyperplasia
  • Liver hemangioma
  • Liver tumor
  • Hepatic adenoma
  • Hepatocellular carcinoma (HCC)
  • Cholangiocarcinoma
  • Benign neoplasm or cancer of the liver
  • Biliary duct tumor
  • Liver or hepatic cyst

Drug induced liver injury

  • Drug- or toxin-induced liver disease

Vascular Anomalies

  • Portal vein thrombosis
  • Abernethy malformation
  • Budd-Chiari syndrome
  • Cavernous transformation of the portal vein
  • Porto-systemic shunt

Other

  • Congenital hepatic fibrosis
  • Hepatomegaly
  • Intestinal failure associated liver disease (IFALD)
  • Gestational alloimmune liver disease
  • Acute liver failure
  • Non-cirrhotic portal hypertension

Heart-liver disease